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目的观察分析无创双水平正压通气治疗新生儿呼吸衰竭的临床效果。方法 80例呼吸衰竭新生儿作为研究对象,根据数字随机分配的原则将其分为观察组与对照组,各40例。对照组患儿给予常规头罩给氧治疗,观察组患儿给予无创双水平正压通气治疗。观察对比两组患儿的临床治疗效果。结果治疗1 h后观察组动脉血氧分压(PaO_2)为(78.3±20.0)mm Hg(1 mm Hg=0.133 kPa)、动脉血二氧化碳分压(PaCO_2)为(36.5±11.2)mm Hg,均优于对照组的(53.4±11.5)、(42.4±10.9)mm Hg,差异均具有统计学意义(P<0.05)。观察组患儿呼吸功能恢复正常所需时间、平均住院时间分别为(54.2±6.6)h、(6.1±1.7)d,均短于对照组的(69.0±13.8)h、(9.6±2.6)d,差异均具有统计学意义(P<0.05)。结论无创双水平正压通气治疗新生儿呼吸衰竭具有良好的临床疗效。
Objective To observe the clinical effect of noninvasive bi-level positive pressure ventilation on neonatal respiratory failure. Methods Eighty newborn infants with respiratory failure were divided into the observation group and the control group according to the principle of random distribution of numbers, 40 cases in each group. The control group of children given conventional hood oxygen therapy, observation group of children given non-invasive bi-level positive pressure ventilation treatment. The clinical effects of two groups were observed and compared. Results PaO2 was (78.3 ± 20.0) mm Hg (1 mm Hg = 0.133 kPa) and PaCO_2 was (36.5 ± 11.2) mm Hg in the observation group at 1 hour after treatment (53.4 ± 11.5) and (42.4 ± 10.9) mm Hg in the control group, the difference was statistically significant (P <0.05). The average duration of respiration in the observation group was (54.2 ± 6.6) h and (6.1 ± 1.7) days, respectively, which were both shorter than those in the control group (69.0 ± 13.8 and 9.6 ± 2.6 days, respectively) , The differences were statistically significant (P <0.05). Conclusion Noninvasive bi-level positive pressure ventilation has good clinical efficacy in neonatal respiratory failure.