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应用３Ｈ－ＴｄＲ掺入法作Ｔ淋巴细胞转化试验，观察了１６５例原发性肝癌患者的细胞免疫功能，并以６３例健康人作对照。结果表明：患者Ｔ淋巴细胞转化力较健康人明显低下，其ＣＰＭ与ＳＩ值均低于健康人，差异非常显著（Ｐ＜０．０１）；Ⅲ期患者ＣＰＭ与ＳＩ均低于Ⅱ期患者，差异非常显著（Ｐ＜０．０１）；治疗有效者ＣＰＭ与ＳＩ升高，无效者则降低；ＣＰＭ与ＳＩ值接近正常者预后好、生存期长，严重低下者则预后差，生存期短。提示原发性肝癌患者细胞免疫功能低下，３Ｈ－ＴｄＲ掺入法Ｔ淋巴细胞转化试验不失为测定原发性肝癌患者细胞免疫功能的重要方法与可靠指标，能为判断病程、疗效、预后及制订治疗方案提供帮助。
The 3H-TdR incorporation method was used for T lymphocyte transformation test. The cellular immune function of 165 patients with primary liver cancer was observed and compared with 63 healthy subjects. The results showed that the T-lymphocyte transforming power of patients was significantly lower than that of healthy people. The CPM and SI values of the patients were lower than those of healthy people (P<0.01). The CPM and SI of patients in stage III were lower than those in stage II patients. The difference was very significant (P<0.01); CPM and SI were elevated in patients with effective treatment, and those who were ineffective were decreased; those with CPM and SI values that were close to normal had a good prognosis and long survival time, and those with severe low had poor prognosis and short survival period. It suggests that the cellular immune function of patients with primary liver cancer is low, 3H-TdR incorporation T lymphocyte transformation test is an important method and reliable indicator for the determination of cellular immune function in patients with primary liver cancer, can determine the course of disease, efficacy, prognosis and treatment The program helps.