介绍生物碱的性质,阐述了生物碱的不同提取方法,如水提取法、酸性水溶液提取法、碱性水溶液提取法、有机溶剂提取法、冷浸提法、回流提取法、索氏提取法、超声波提取法、膜提取法、超临界提取法。比较不同提取方法提取苦丁茶生物碱的优缺点,采用超临界萃取法提取生物碱的提取工艺,确立最优提取条件。 The properties of alkaloids were introduced. Different extraction methods of alkaloids were introduced, such as water extraction, acidic aqueous extraction, alkaline aqueous extraction, organic solvent extraction, cold extraction, reflux extraction, Soxhlet extraction, ultrasonic Extraction, membrane extraction, supercritical extraction method. The advantages and disadvantages of different extraction methods for extracting kudingcha alkaloids were compared. The extraction process of alkaloids by supercritical extraction was optimized and the optimal extraction conditions were established.