脑膜感染是中枢神经系统常见的感染性疾病。既往的研究多注重于外来病原对宿主的影响 ,近年来随着分子生物学和免疫学的飞速发展 ,宿主对感染的自身反应已得到重视。细菌及其成分可刺激中枢神经系统在局部产生各种细胞因子 ,引发体内一系列反应 ,其中白细胞介素Ｉｎｔｅｒｌｅ Meningeal infection is a common infectious disease of the central nervous system. Previous studies have focused more on the impact of foreign pathogens on the host, in recent years with the rapid development of molecular biology and immunology, host response to infection has been valued. Bacteria and their components can stimulate the central nervous system in the local generation of various cytokines, triggering a series of reactions in vivo, including interleukin Interle