目的评价准分子激光角膜切削术（ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅｋｅｒａｔｅｃｏｍｙ，ＰＲＫ）治疗低、中度近视的远期疗效。方法对１４８只眼屈光度为－１５０～－６００ＤＰＲＫ术后５年以上患者的视力、屈光度及角膜曲率进行随访观察。结果ＰＲＫ术后５年未矫正视力≥１０者１３６只眼（９１９％），０８者４只眼（２７％），≥０６者８只眼（５４％）。术后等值球镜（－０１２±０２２）Ｄ，角膜曲率Ｋ值术前（４３８１±１１０）Ｄ，术后（４１３６±１３０）Ｄ两者间比差异有显著性（Ｐ＜００１）。结论ＰＲＫ治疗低、中度近视的远期疗效可靠。 Objective To evaluate the long-term efficacy of photorefractive keratectomy (PRK) in the treatment of low and moderate myopia. Methods Visual acuity, refraction and corneal curvature were observed in 148 eyes with refractive power of -150 ~ -600 DPRK more than 5 years after operation. Results There were 136 eyes (919%) with visual acuity≥10, 4 eyes with 08 (27%), 8 eyes ≥6 %). Postoperative spherical equivalent (-0.12 ± 0.22) D, corneal curvature K (4381 ± 110) D and postoperative (4136 ± 1.30) D The difference was significant (P <001). Conclusion PRK treatment of low and moderate myopia long-term efficacy and reliable.