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建立反相高效该相色谱法（HPLC）同时测定强力苷口服液中甘草酸铵和肌苷含量。HPLC条件为．岛津ShimpackCLG－ODS（150×4．6mm）柱，流动相为甲醇－水（70：30），紫外检测波长252nm。结果甘草酸铵浓度线性范围10～100μg／ml（r＝0．9990），平均口收率为98．25％，RSD＝0．5％；肌苷浓度线性范围50～500μg／ml（r＝0．9999），平均回收率为99．87％，RSD＝0．4％．
An RP-HPLC method was developed for the simultaneous determination of ammonium glycyrrhizinate and inosine in tolidine oral solution. The HPLC conditions are. Shimadzu ShimpackCLG-ODS (150 × 4.6mm) column, the mobile phase methanol-water (70:30), UV detection wavelength of 252nm. Results The linear range of glycyrrhizin was 10 ~ 100μg / ml (r = 0.9990), the average oral yield was 98.25% with RSD 0.5%. The linear range of inosine concentration was 50 ~ 500μg / ml (r = 0.9999). The average recovery was 99.87%, RSD = 0.4%.