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肺癌是人类最常见的恶性肿瘤之一,75%患者就诊时已经失去手术机会,化疗成为主要的治疗手段,导致化疗失败的主要原因是肿瘤细胞产生多药耐药。所谓多药耐药(multidrug resistance,MDR)是指肿瘤细胞对一种药物抗药时,对其他一些结构不同,作用机制不同的药物也具有抗药性。MDR的机
Lung cancer is one of the most common human malignant tumors. 75% of the patients have lost the chance of surgery at the time of treatment. Chemotherapy has become the main treatment. The main reason for the failure of chemotherapy is that the tumor cells produce multi-drug resistance. The so-called multidrug resistance (multidrug resistance, MDR) refers to the tumor cells to a drug resistance, to some other structures, different mechanisms of action of the drug also has resistance. MDR machine