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光相干断层扫描(OCT)具有非接触性、可重复性好、获取眼部图像快等优点,随着OCT图像分辨率和扫描速度的不断提高,以及从时域OCT(TD-OCT)到频域OCT(SD-OCT)的发展,使其在眼科领域的应用越来越广泛.在原发性青光眼的诊断中,OCT从对视野出现损害的中晚期青光眼的诊断已经发展到可以对视野损害前的青光眼进行诊断,尤其是在原发性开角型青光眼(POAG)病程进展的随访检查中起到重要作用.近年来,通过检测视网膜神经纤维层(RNFL)厚度、视盘结构参数以及对黄斑区视网膜神经节细胞复合体(mGCC)厚度进行测量,SD-OCT对青光眼的检测和诊断作出了巨大的贡献.本文对SD-OCT检测以上参数在原发性青光眼诊断中的应用研究进展进行综述.“,”Optical coherence tomography (OCT) has the advantage of non-contact,good repeatability and quick to obtain retinal image.With the rapid development of resolution and scanning speed,OCT has been more widely used in the field of ophthalmology.OCT has developed from time-domain OCT (TD-OCT) to spectral-domain OCT (SD-OCT).OCT can diagnose glaucoma without visual field damage and play an important role in monitoring and diagnosing the progression of primary open angle glaucoma.In recent years,SD-OCT has made an enoumous contribution to the detection and diagnosis of glaucoma,by detecting retinal nerve fiber layer (RNFL) thickness,structural parameters of optic disc as well as the macular ganglion cell complex (mGCC) thickness.This paper reviewed the relevant researches of the three parameters obtained from SD-OCT on the diagnosis of primary glaucoma.