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目的 :建立乙酰螺旋霉素效价测定培养基的改进方法。方法 :以麦迪 (白 )霉素专用培养基中加入适量葡萄糖进行效价测定。结果 :与《中国药典》2 0 0 0年版方法比较 ,无显著性差异 (P >0 .0 5 )。结论 :改进法操作方便 ,结果准确可靠 ,适用于乙酰螺旋霉素的效价测定。
OBJECTIVE: To establish an improved method for the determination of acetylspiramycin titer culture medium. Methods: The titer of glucose was determined by adding appropriate amount of dextrose to the media of Trabmex. Results: Compared with the Chinese Pharmacopoeia 2000 edition, there was no significant difference (P> 0.05). Conclusion: The improved method is easy to operate and the results are accurate and reliable. It is suitable for the determination of the titer of acetylspiramycin.