19世纪末,欧洲人在防治葡萄霜霉病时偶然发现波尔多液能伤害一些十字花科杂草而不伤害禾谷类作物。1895年,法德美等国几乎同时发现硫酸铜具有选择性除草作用。于是利用无机盐作为除草剂防除杂草的方法就发展起来了,从此拉开了研制化学除草剂的序幕。 By the late 19th century, Europeans occasionally discovered that Bordeaux mixture could damage some cruciferous weeds while preventing grape downy mildew without harming cereal crops. In 1895, France and Germany and other countries almost simultaneously found that copper sulfate has a selective herbicidal effect. So the use of inorganic salts as herbicides to control weeds developed, and from there opened the prelude to the development of chemical herbicides.