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目的探讨内镜治疗慢性胰腺炎(CP)的治疗效果。方法研究自1997年1月至2004年12月期间在上海长海医院确诊为 CP,并住院行内镜治疗的患者,随访观察其临床疗效。结果符合 CP 诊断标准并进行内镜下治疗的患者共296例。其中胰管括约肌单纯切开23例,胰头部胰管气囊扩张11例,胰管取石86例。138例放置主胰管支架,26例放置副胰管支架。EUS 下经胃壁假性囊肿引流12例,EUS 下腹腔神经节阻滞30例。224例患者腹痛症状均有不同程度缓解(P<0.05),1周后148例患者腹痛症状缓解,其中34例(15.2%)腹痛缓解持续时间达7年。患者内镜治疗成功率100%,无严重并发症发生,体质量均有一定程度增加(P<0.05)结论内镜治疗能有效缓解 CP 患者的腹痛症状,增加患者的体质量,是治疗 CP 的一种安全有效的手段。
Objective To investigate the therapeutic effect of endoscopic treatment of chronic pancreatitis (CP). Methods From January 1997 to December 2004 in Shanghai Changhai Hospital diagnosed as CP, and hospitalized patients with endoscopic treatment, follow-up observation of its clinical efficacy. Results In line with the CP diagnostic criteria and endoscopic treatment of patients a total of 296 cases. Including pancreatic sphincter simple incision in 23 cases, pancreatic head pancreatic duct balloon dilatation in 11 cases, 86 cases of pancreatic duct stone. 138 cases placed the main pancreatic duct stent, 26 cases placed pancreatic duct stent. EUS underwent gastric wall pseudocyst drainage in 12 cases, 30 cases of EUS under celiac ganglia block. The symptoms of abdominal pain in 224 patients were relieved to varying degrees (P <0.05). One week later, 148 patients were relieved of abdominal pain symptoms, of which 34 (15.2%) had abdominal pain relief lasting for 7 years. The endoscopic success rate was 100%, no serious complication occurred, the body weight increased to a certain degree (P <0.05). Conclusion Endoscopic treatment can effectively relieve the symptoms of abdominal pain in patients with CP and increase the body weight of patients with CP A safe and effective means.