论文部分内容阅读
中药物质基础复杂,对其活性成分的分离一直是中药研究的难题。基于高压制备液相的多维色谱系统在高压制备液相色谱的基础上,结合了多种分离技术,极大地提高了色谱系统的分离性能和分离效率,更有利于对物质基础复杂的中药样品进行分离纯化。本文介绍了基于高压制备液相系统的多维色谱系统的基本原理、分离模式以及关键技术,并综述了其在中药分离纯化中的应用。
The basis of traditional Chinese medicine is complex, the separation of its active ingredients has always been a problem of traditional Chinese medicine research. Based on high pressure liquid chromatography, a multi-dimensional chromatographic system based on high pressure liquid phase is combined with a variety of separation techniques to greatly improve the separation performance and separation efficiency of the chromatographic system, which is more conducive to the traditional Chinese medicine samples with complex material basis Isolation and Purification. This paper introduces the basic principle, separation mode and key technologies of multidimensional chromatography system based on high pressure liquid phase preparation system. The application of the method in the separation and purification of traditional Chinese medicine is reviewed.