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目的:评价南京市抗酸及治疗消化性溃疡病药物的应用状况及趋势。方法:采用金额排序法和用药频度排序法,对南京市22家医院2003年~2005年抗酸及治疗消化性溃疡病药物用药数据进行统计分析。结果:3年中此类药物的用药金额呈逐年上升趋势,平均年增长率达30.8%;奥美拉唑用药频度增长显著,平均年增长率为36.8%。结论:随着消化性溃疡病发病率的增加,疗效确切、副作用少、不良反应发生率低、用药依从性好的质子泵抑制剂已成为临床首选,其用药金额构成比逐年增加。
Objective: To evaluate the application status and trends of antacid and peptic ulcer disease in Nanjing. Methods: The data of drug usage of antacid and peptic ulcer disease in 22 hospitals in Nanjing from 2003 to 2005 were statistically analyzed by the method of order of amount and frequency of medication. Results: The dosage of these drugs increased year by year with an average annual growth rate of 30.8%. The frequency of omeprazole medication increased significantly with an average annual growth rate of 36.8%. Conclusion: With the increase of the incidence of peptic ulcer disease, the curative effect is definite, the side effects are few and the incidence of adverse reactions is low. The proton pump inhibitor with good compliance has become the first choice of clinical practice.