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血栓性血小板减少性紫癜(TTP)是由于微循环血管内弥散性血栓形成,导致微循环阻塞而产生的一种综合征,主要症状包括溶血性贫血、血小板减少、神经症状、发热和肾功能损害。TTP可分为遗传性和获得性两类。大部分获得性TTP主要是由自身抗体介导,故称为免疫性TTP。1病因与发病机制T
Thrombotic thrombocytopenic purpura (TTP) is a syndrome that results from microcirculation of diffuse thrombosis leading to obstruction of the microcirculation. The main symptoms include hemolytic anemia, thrombocytopenia, neurological symptoms, fever and impaired renal function . TTP can be divided into two types of genetic and acquired. Most of the acquired TTP is mainly mediated by autoantibodies, it is called immune TTP. Etiology and pathogenesis