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目的探讨高频超声联合乳腺数字化钼靶X线摄影在乳腺肿块诊断中的价值。方法乳腺肿块患者116例(121个肿块),均于术前7d行乳腺高频超声、钼靶X线摄影检查,与手术或超声引导下穿刺活检组织病理结果进行对照,比较高频超声、钼靶X线单独及联合诊断乳腺肿块的准确性、敏感性、特异性。结果组织病理诊断良性肿块37个,恶性肿块84个;高频超声诊断良性肿块42个,恶性肿块79个;钼靶X线诊断良性肿块64个,恶性肿块57个;高频超声联合钼靶X线诊断良性肿块46个,恶性肿块75个;以组织病理结果为标准,高频超声诊断乳腺肿块的准确性为62.8%、敏感性为70.2%、特异性为45.9%、阳性预测值为74.7%、阴性预测值为40.5%、假阳性率为54.1%、假阴性率为29.8%,钼靶X线分别为56.2%、52.4%、64.9%、77.2%、37.5%、35.1%、52.4%,高频超声联合钼靶X线分别为76.0%、77.4%、73.0%、86.7%、58.7%、27.0%、22.6%;高频超声联合钼靶X线诊断乳腺肿块的准确性、敏感性、阳性预测值和阴性预测值高于高频超声、钼靶X线,特异性高于高频超声、假阳性率低于高频超声,差异均有统计学意义(P<0.05)。结论高频超声和钼靶X线在乳腺肿块诊断中各具优势,二者联合可优劣互补,提高诊断准确率。
Objective To investigate the value of high frequency ultrasound combined with mammography digital mammography in the diagnosis of breast masses. Methods One hundred and sixty-one patients (121 lumps) with breast masses were examined by high-frequency mammography and mammography at 7 days before operation. The results were compared with histopathological results of biopsy guided by surgery or ultrasound. Accuracy, sensitivity and specificity of target X-ray diagnosis of breast masses alone and in combination. Results There were 37 benign tumors and 84 malignant tumors in histopathological diagnosis. Forty-two benign tumors were diagnosed by high-frequency ultrasound and 79 malignant tumors. Sixty-four benign tumors and 57 malignant tumors were diagnosed by mammography. High-frequency ultrasound combined with molybdenum target X According to histopathological results, the accuracy of high-frequency ultrasound in the diagnosis of breast masses was 62.8%, the sensitivity was 70.2%, the specificity was 45.9%, and the positive predictive value was 74.7% , The negative predictive value was 40.5%, the false positive rate was 54.1%, the false negative rate was 29.8%, the mammography X-ray was 56.2%, 52.4%, 64.9%, 77.2%, 37.5%, 35.1%, 52.4% The accuracy of ultrasound and mammography in the diagnosis of breast masses was 76.0%, 77.4%, 73.0%, 86.7%, 58.7%, 27.0% and 22.6% respectively. The accuracy, sensitivity and positive predictive value The values of the negative predictive value and the negative predictive value were higher than those of the high-frequency ultrasound, the mammography X-ray, the specificity higher than the high-frequency ultrasound, the false positive rate was lower than the high-frequency ultrasound, the difference was statistically significant (P <0.05). Conclusion High-frequency ultrasound and mammography X-ray have their own advantages in the diagnosis of breast lumps, the combination of the two can be advantages and disadvantages, improve diagnostic accuracy.