大剂量维 C 静注治疗急性重症克山病显效及硒预防克山病成功是克山病研究工作中的两大突破。目前的研究认为硒预防克山病的生化机理是硒提高了体内 GSH—Px 活性,保护了生物膜免遭脂质过氧化损害。但对大剂量维 C 治疗有效的生化机制 Large doses of vitamin C intravenous treatment of acute severe Keshan disease and selenium effective prevention Keshan disease is Keshan disease research work in the two major breakthroughs. The current study suggests that selenium prevents Keshan disease biochemical mechanism is that selenium increases GSH-Px activity in vivo, protecting the biofilm from lipid peroxidation damage. However, high-dose vitamin C treatment of effective biochemical mechanisms