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目的分析紫癜性肾炎病理类型与临床特征的相关性。方法收集医院2010年11月-2013年11月诊治的紫癜性肾炎患者60例作为研究对象,采用回顾性的方式分析患者的临床资料,总结肾炎病理类型与临床的相关性。结果本组患者中肾病综合征9例(30.0%),位居首位,其次蛋白尿与血尿型8例(26.67%),尿检正常型5例(16.67%),孤立性蛋白尿或血尿型4例(13.33%),血尿加肾病综合征型3例(10.0%),另外肾炎综合征型1例(3.33%)。同时合并Ig A、Ig M、Ig G沉积患者在病理类型上与单纯Ig A沉积患者比较程度更深。结论单纯的Ig A沉积类型,则其病理改变往较轻,如果患者为Ig A合并有Ig M沉积,或者同时为Ig A、Ig M、Ig G沉积,则患者的病理改变往往较重。
Objective To analyze the correlation between pathological types and clinical features of purpuric nephritis. Methods 60 cases of purpuric nephritis diagnosed and treated in the hospital from November 2010 to November 2013 were collected. The clinical data of the patients were analyzed retrospectively. The pathological types of nephritis and clinical correlation were summarized. Results The nephrotic syndrome in this group was 9 cases (30.0%), ranking the first place, followed by proteinuria and hematuria in 8 cases (26.67%), urinalysis in 5 cases (16.67%), isolated proteinuria or hematuria type 4 (13.33%), 3 cases of hematuria and nephritic syndrome (10.0%), and 1 nephritis syndrome (3.33%). Patients with concurrent Ig A, Ig M, Ig G deposits also had a lesser degree of histopathology than patients with Ig A alone. Conclusions Pure IgA deposition types are less pathological, with pathological changes often heavier in patients with IgA with or without IgA, IgM, and IgG deposition.