为了从传统中药中寻找防治化疗和放疗所致骨髓粒系造血抑制的药物，通过建立实验性环磷酰胺（Cy：0．08g／kg）低白细胞血症小鼠模型，观察了参芪补苦复方（GAFS：13．9g／kg·dip6d）对粒系造血的影响。结果表明：GAFS对Cy所致外周血白细胞和中性粒细胞数下降具有对抗和促恢复作用（P＜0．01），能防治骨髓有核细胞数、粒-巨噬系祖细胞（CFU－GM）数的减少（P＜0．01），促进CFU－GM增殖并诱导其向粒系、巨噬系分化，且其促粒系造血作用优于鲨肝醇。 In order to search for traditional Chinese medicine for the prevention and treatment of bone marrow granulocytic hematopoietic suppression caused by chemotherapy and radiotherapy, an experimental cyclophosphamide (Cy: 0.08 g/kg) low leukocyte model was established to observe the effects of ginseng supplementation. The effect of compound (GAFS: 13.9 g/kg·dip6d) on hematopoiesis. The results showed that GAFS had anti- and recovery effect on the decrease of white blood cells and neutrophils in peripheral blood induced by Cy (P<0.01), and could prevent bone marrow nucleated cells and granulocyte-macrophage progenitor cells (CFU- The decrease in the number of GM (P<0.01) promoted the proliferation of CFU-GM and induced its differentiation into granulocytes and macrophages, and its hematopoietic effect was better than shark hepatol.