曲马多是一种与阿片类镇痛药结构相似的镇痛药,但又有其不同的特点。最初在德国上市,现已销往几十个国家。本文拟从曲马多的药理作用及临床应用方面加以阐述。1.药理作用 曲马多属于μ—阿片受体激动剂,但它又不表现出典型的阿片类药物的副作用如呼吸抑制、镇静 Tramadol is an analgesic similar in structure to opioid analgesics, but has different characteristics. Originally listed in Germany, it is now sold in dozens of countries. This article intends to elaborate from the tramadol pharmacological effects and clinical application. 1. Pharmacological effects Tramadol is a μ-opioid receptor agonist, but it does not exhibit the typical opioid side effects such as respiratory depression, sedation