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With the widespread clinical application of renal biopsy and serum antineutrophil cytoplasmic antibody (ANCA) testing, the percentage of renal injuries caused by systemic small vessel vasculitis (SVV) including microscopic polyangiitis (MPA) and Wegener’ s granulomatosis (WG) is on the rise in China. According to our previous report, SVV constituted 1.09% of diagnoses from all renal biopsies (5. 8% in secondary nephritis) and 14. 4% of that from renal biopsies from patients with chronic renal,failure, among which MPA is the most common type. Many studies reported that SVV with rapid progressive glomerulonephritis had poor prognosis with a 5-year renal survival less than 75%. However, there is a lack of large-sample statistical analysis about the long-term prognosis of SVV in China. Indeed, the clinical manifestations of SVV in China are quite different from those reported in other countries. This study is a retrospective analysis of the long term patient and renal survival rate and contributing factors based on 60 cases of MPA.
With the widespread clinical application of renal biopsy and serum antineutrophil cytoplasmic antibody (ANCA) testing, the percentage of renal flora caused by small small vessel vasculitis (SVV) including microscopic polyangiitis (MPA) and Wegener’s granulomatosis (WG) is on the rise According to a previous report, SVV comprised 1.09% of diagnoses from all renal biopsies (5.8% in secondary nephritis) and 14. 4% of that from renal biopsies from patients with chronic renal failure, among which MPA is the most common type. Many studies reported that SVV with rapid progressive glomerulonephritis had poor prognosis with a 5-year renal survival less than 75%. However, there is a lack of large-sample statistical analysis about the long-term prognosis of SVV in China. Indeed, the clinical manifestations of SVV in China are quite different from those reported in other countries. This study is a retrospective analysis of the long term patient and renal survival rate and con tributing factors based on 60 cases of MPA.