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目的 :探讨甘氨酰脯氨酸二肽氨基肽酶 (GPDA-F/ALT)、r-谷氨酰转肽酶 (GGT- )和甲胎蛋白 (AFP)联合检测对肝癌的诊断价值。方法 :对 10 8例肝癌和 130例良性肝病患者进行了 GPDA-F/AL T、GGT-II和 AFP3项指标联合检测 ,分析这些指标对肝癌的互补诊断价值。结果 :肝癌患者 GPDA-F/ALT、GGT-II和 AFP3项指标均高于良性肝病 ;GPDA-F/ALT与GGT-II和 AFP之间无相关性 ;3项指标同步检测可明显提高肝癌的诊断敏感性。结论 :GPDA-F/ALT、GGT-II和 AFP3项指标对肝癌有互补诊断价值 ,联合检测能提高肝癌的诊断水平。
Objective: To investigate the diagnostic value of GPDA-F / ALT, GGT- and AFP in the diagnosis of liver cancer. Methods: The combined detection of GPDA-F / ALT, GGT-II and AFP3 in 108 patients with hepatocellular carcinoma and 130 patients with benign liver disease was performed. The diagnostic value of these indexes in the diagnosis of HCC was analyzed. Results: The indexes of GPDA-F / ALT, GGT-II and AFP3 in patients with liver cancer were higher than those in patients with benign liver disease. There was no correlation between GPDA-F / ALT and GGT-II and AFP. Diagnostic sensitivity. Conclusion: GPDA-F / ALT, GGT-II and AFP3 indicators of complementary diagnostic value of liver cancer, combined detection can improve the diagnosis of liver cancer.