目的:探讨全面健康管理对代谢综合征患者早期肾功能不全发展影响。方法:随机选取2016年5月至2017年1月在南京市第一医院接受治疗代谢综合征患者的患者100名,按患者来到医院就诊的先后顺序,将其分为对照组及观察组,两组患者分别采取不同干预方式,对于对照组的患者,实施普通的干预模式,而观察组的患者,采取不同的模式,为其实施全面健康管理,分别观察两组患者在采取不同干预模式后的尿微量白蛋白情况。结果:在研究结束后的6个月,观察组代谢综合征患者的尿微量白蛋白数值(15.75±2.64)mg/L明显低于常规对照组代谢综合征患者的尿微量白蛋白数值(17.45±2.83)mg/L,两组差别有统计学意义。结论:全面健康管理方式,对患者的肾功能的保护具有一定的作用,值得在临床上推广。 Objective: To investigate the impact of general health management on the development of early renal dysfunction in patients with metabolic syndrome. METHODS: A total of 100 patients with metabolic syndrome who were treated in Nanjing No.1 Hospital from May 2016 to January 2017 were randomly selected. According to the order in which the patients came to the hospital for treatment, they were divided into control group and observation group. The two groups of patients took different interventions, for the control group of patients, the implementation of common intervention mode, while the observation group of patients, take a different model for its implementation of a comprehensive health management, were observed in two groups of patients after taking different intervention modes Urine microalbumin case. Results: At 6 months after the study, urinary microalbuminuria (15.75 ± 2.64) mg / L in patients with metabolic syndrome in the observation group was significantly lower than that in the patients with metabolic syndrome in the control group (17.45 ± 2.83) mg / L, the difference between the two groups was statistically significant. Conclusion: The comprehensive health management mode has a certain effect on the protection of renal function in patients and is worth popularizing clinically.