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雷尼替丁为 H_2受体拮抗剂,其口服制剂在治疗上消化道出血时,常发生困难,疗效不理想,而静注或肌注时却能达到迅速止血的目的,为此开发丁注射剂。同时,作为麻醉前给药,只有注射剂才是适宜的。1.药理作用雷尼替丁具组胺 H_2受体拮抗作用,能抑制胃液分泌而防止胃内 PH 值过低,故可用作预防出血以至止血。由于本品为注射剂,不需经口服给药而影响胃液分泌,通过对各种实验性溃疡及出血动物摸型进行的血液凝固及血小扳凝象作用的试验,
Ranitidine is a H 2 receptor antagonist, its oral preparation in the treatment of upper gastrointestinal bleeding, often difficult, curative effect is not ideal, but intravenous or intramuscular injection but can achieve the purpose of rapid hemostasis, for which the development of small injection . At the same time, only injections are suitable as pre-anesthetic administration. 1. pharmacological effects Ranitidine H 2 receptor antagonist with histamine can inhibit the secretion of gastric juice to prevent the PH value in the stomach is too low, it can be used as a hemostasis to prevent bleeding. Because this product is injection, without oral administration of gastric juice secretion, through a variety of experimental ulcer and bleeding animal touch of blood coagulation and blood platelet coagulation test effect,