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利凡诺(Rivanol)是二十年代合成的抗菌药物,对多种革兰氏阳性与阴性细菌都有抗菌作用,故目前仍用作外用消毒杀菌剂。早在1948年国外就试用利凡诺于中期妊娠引产,获得成功。自1958年以来,国内北京、重庆、沈阳等地也相继试用,有效率高达97%。如剂量适当,注意禁忌症,并无毒性反应。因此,近年来利凡诺中孕引产已在我国许多地区得到推广。然而,有关此药对子宫的作用迄今尚无全面系统的研究。据报导利凡诺能兴奋离休豚鼠子宫(已孕或未孕不详,对离体和在体已孕家兔子宫的作用以兴奋为主,但对离体未孕大白鼠子宫则有抑制作用。
Rivanol is an antibacterial agent synthesized in the 1920s and has antibacterial activity against many Gram-positive and -negative bacteria. Therefore, Rivanol is still used as topical disinfectant. As early as 1948 abroad, trial of Rivanol in mid-term pregnancy induction of labor was successful. Since 1958, domestic Beijing, Chongqing, Shenyang and other places have also been trial, the efficiency as high as 97%. If the dose is appropriate, pay attention to contraindications, and no toxic reaction. Therefore, in recent years, Rivrovano pregnant induction has been promoted in many areas of our country. However, there is no comprehensive systematic study on the effect of this medicine on the uterus. It is reported that Levano can be excited to leave the guinea pig uterus (pregnant or non-pregnant unknown, in vitro and in vivo have the role of pregnant rabbits uterus to stimulate the main, but there is no inhibitory effect on isolated uterus of pregnant rats.