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本文研究了５０ｍｇ石英粉尘一次性气管内注入式染尘的同时、染尘后１个月及３个月气管内注入柠檬酸铝（含铝１０ｍｇ）对大鼠矽肺的防治效果。结果表明：给铝对染尘所致肺灌洗液细胞中羟脯氨酸、总脂，上清液中总脂、总蛋白、乳酸脱氢酶、铜蓝蛋白，甚至全肺胶原等指标的改变均表现有一定抑制作用；且给铝时间越早，效果越好。说明经气管向肺内直接给药可能是治疗矽肺的一种有效途径。
In this paper, we studied the prevention and treatment of silicosis by injecting aluminum citrate (containing 10 mg of aluminum) intratracheal intratracheal intratracheal intratracheal instillation of 50mg quartz dust in one-time intratracheal instillation and dusting at 1 month and 3 months after the dying. The results showed that the content of hydroxyproline, total lipid, total lipid, total protein, lactate dehydrogenase, ceruloplasmin and even whole lung collagen in lung lavage fluid induced by aluminum Change showed a certain inhibition; and the earlier the aluminum, the better. That the direct tracheal administration to the lungs may be an effective way to treat silicosis.