由于结构特征阻碍了口服头孢菌素的发展。目前,临床有用的口服头孢菌素很少。一般口服头孢菌素在抗菌活性方面同肠胃外给予头孢菌素相同,但是在药理学性质却有所不同。新的口服头孢菌素LY163892具有广谱抗菌活性。作者以529株新分离菌株进行体外抗菌活性观察,同时与头孢克罗(Cefaclor)、头孢拉定(Cephradine)、头孢氨 Due to structural features impede the development of oral cephalosporins. Currently, there are few clinically useful oral cephalosporins. Oral cephalosporins generally have the same antimicrobial activity as cephalosporins administered parenterally, but differ in their pharmacological properties. The new oral cephalosporin LY163892 has a broad spectrum of antibacterial activity. The authors in vitro 529 isolates of antibacterial activity in vitro observation, at the same time with cefaclor (Cefaclor), cephradine (Cephradine), cephapirin