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目的探讨来曲唑(LE)和克罗米芬(CC)促排卵的临床疗效.方法将30个周期不孕患者随机分成2组,其中来曲唑组18个周期,氯米芬组12个周期.观察、比较两组hCG日优势卵泡数、子宫内膜的厚度、宫颈黏液评分.结果来曲唑组HCG日优势卵泡数、HCG日子宫内膜厚度、宫颈黏液评分、临床周期妊娠率均优于氯米芬组(P<0.05).结论 LE促排卵可以减少CC抗雌激素样作用对子宫内膜的不良影响,使子宫内膜有较好的容受性,有利于妊娠.“,”Objective:To explore the clinical effects of letrozole (LE) and clomiphene citrate (CC) on ovulation induction. Methods:30 cycles of infertile women were divided into two groups, with 18 cycles in LE group and 12 cycles in CC group. The endometrial thickness and cervical Insler score, dominant folicle numbers in the two groups were observed and compared. Results:LE group had the higher average dominant folicle numbers, endometrial thickness on HCG days, cervical mucus scores and clinical pregnancy rate than CC group(P <0.05). Conclusion:LE can reduce the effect about CC anti-estrogen, improve the endometrical acceptable.