已证实人胎盘存在鸦片肽,但几乎没有资料论证其存在的生物学意义.胎盘中主要的鸦片类似物质强啡肽和β-内啡肽对垂体催乳素(PRL)的分泌有重要调节作用。人胎盘催乳素(hPL)与垂体PRL 的化学结构相似。那么,强啡肽和β-内啡肽对垂体 PRL 分泌与胎盘 hPL 分泌的调控是否也相似呢?为此,本工作观察了妊娠中期或足月胎盘细胞膜的鸦片受体位点。 It has been confirmed that there is opioid peptide in human placenta, but there is little data to prove the biological significance of its existence.Dynorphin and β-endorphin, the major opioid substances in the placenta, play an important regulatory role in the secretion of pituitary prolactin (PRL). Human placental prolactin (hPL) and pituitary PRL chemical structure similar. So, the dynorphin and β-endorphin on pituitary PRL secretion and placental secretion of hPL also regulate the control it? To this end, the work of the second trimester of pregnancy or placental opiate membrane receptor sites.