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脑血管病是引起以痴呆为主的临床疾患的常见病因。而痴呆又常是由于广泛性皮质软化造成的,但偶亦可由皮质下动脉硬化性脑病(SAE)或Bins-Wanger氏病的弥散性白质变性所造成。本文报导一例具有这种罕见脑血管病的临床及病理特征的51岁男性病人,因进行性痴呆一年内6次住院治疗。病人早期表现为淡漠,易倦怠,远及近记忆力减退,不能胜任工作等人格改变,继则出现迅速进展的精神运动性迟缓,括约肌失禁,共济失调,精神错乱,谵妄,失定向力及语无伦次,生活不能自理。神经系统检查:血压间歇性中度升高,除情感,记忆、语言,步态障碍、拱嘴与吸吮反射,括约肌失禁以及晚期出现的全身肌张力增高,运动不能,缄默等明显的弥散性大脑动能障碍外,仅有短暂的,轻度
Cerebrovascular disease is a common cause of clinical conditions that predominate with dementia. Dementia is often caused by extensive cortical softening, but even caused by diffuse white matter degeneration of subcortical arteriosclerotic encephalopathy (SAE) or Bins-Wanger’s disease. This article reports a case of a 51-year-old male patient with the clinical and pathological features of this rare form of cerebrovascular disease who was hospitalized for 6 times a year due to progressive dementia. Patients showed early indifference, easy burnout, far and near memory loss, can not be qualified for work and other personality changes, followed by the rapid progress of mental retardation, sphincter incontinence, ataxia, delirium, delirium, loss of direction and incoherent , Life can not take care of themselves. Nervous system examination: moderately elevated blood pressure intermittent, in addition to emotion, memory, language, gait disorders, arch mouth and sucking reflex, sphincter incontinence, and later systemic hypertrophy, motor failure, silence and other significant diffuse brain Momentum disorders, only short-term, mild