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目的探讨发作性睡病并阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopneasyndrome,OSAHS)的发病机制、临床特点及治疗。方法回顾性分析1例发作性睡病并OSAHS患者的临床表现、多导睡眠图及颅脑MRI检查,并复习相关文献。结果患者有白天过度睡眠、嗜睡猝倒发作、睡眠麻痹和睡眠幻觉,睡眠呼吸监测提示严重呼吸暂停低通气表现,颅脑MRI检查示脑内多发腔隙灶及蛛网膜囊肿。结论发作性睡病与OSAHS可能相互影响,两病共存并非罕见,应避免漏诊。
Objective To investigate the pathogenesis, clinical features and treatment of narcolepsy and obstructive sleep apnea hypopnea syndrome (OSAHS). Methods Retrospective analysis of 1 case of narcolepsy and OSAHS patients with clinical manifestations, polysomnography and brain MRI examination, and review the relevant literature. Results Patients had excessive daytime sleepiness, lethargy cataplasm attack, sleep paralysis and sleep hallucinations, sleep apnea monitoring showed severe apnea hypopnea performance, brain MRI showed multiple intracranial lacunar and arachnoid cysts. Conclusion Narcolepsy and OSAHS may interact with each other and coexistence of the two diseases is not uncommon and should be avoided.