目的探讨经尿道等离子体双极电切术(TUPKBt)治疗膀胱肿瘤的临床疗效。方法选择我院2009年1月～2012年12月治疗的50例膀胱肿瘤患者,随机分成实验组和对照组,各25例,实验组给予经尿道双极等离子体膀胱肿瘤电切术,对照组给予膀胱部分切除术,两组术后均行持续膀胱冲洗和膀胱灌注盐酸比柔吡星化疗。结果实验组手术时间为(26.9±5.5)min,术中出血量为(31.1±5.1)ml,平均住院时间(5.0±1.7)d,对照组手术时间为(81.5±15.8)min,术中出血量为(101.1±18.6)ml,平均住院时间(11.2±2.5)d,实验组明显低于对照组,两组比较有显著性差异(P<0.05),实验组共发生并发症2例,并发症发生率为8.0%,其中尿道狭窄1例,不稳定膀胱症状1例;对照组发生并发症8例,并发症发生率为32.0%,尿道狭窄1例,伤口感染2例,膀胱穿孔2例,不稳定膀胱症状3例,实验组明显低于对照组,两组比较有显著性差异(P<0.05)。结论经尿道等离子体双极电切术治疗膀胱肿瘤,手术时间短、术中出血少,并发症少,疗效显著,值得推广。 Objective To investigate the clinical efficacy of transurethral plasma bipolar grafting (TUPKBt) in the treatment of bladder cancer. Methods Fifty patients with bladder cancer who were treated in our hospital from January 2009 to December 2012 were randomly divided into experimental group and control group, with 25 cases in each group. The experimental group was given transurethral resection of transurethral bipolar plasma bladder tumor and the control group Partial partial resection of the bladder was performed. Both patients underwent continuous bladder irrigation and intravesical instillation of buprenorphine hydrochloride compared with that of buprenorphine. Results The operation time of the experimental group was (26.9 ± 5.5) min, the blood loss was (31.1 ± 5.1) ml and the average length of hospital stay was 5.0 ± 1.7 days, while the control group was (81.5 ± 15.8) min and the intraoperative bleeding (101.1 ± 18.6) ml and average length of hospital stay (11.2 ± 2.5) d, the experimental group was significantly lower than the control group, there was significant difference between the two groups (P <0.05) The incidence of disease was 8.0%, including 1 case of urethral stricture and 1 case of unstable bladder symptoms. Complication occurred in 8 cases in control group, the complication rate was 32.0%, urethral stricture in 1 case, wound infection in 2 cases, bladder perforation in 2 cases , Unstable bladder symptoms in 3 cases, the experimental group was significantly lower than the control group, there was a significant difference between the two groups (P <0.05). Conclusions Transurethral plasma bipolar resection for bladder cancer has short operative time, less intraoperative bleeding, fewer complications and significant curative effect. It is worth to be popularized.