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各种药物单独作用于人体,可产生各自的药理效应。当多种药物联合应用时,由于它们的相互作用,可使药效加强或副作用减轻,也可使药效减弱或出现不应有的毒副作用,甚至可出现一些特异的不良反应,危害用药者。从目前水平来看,多数情况下只能探讨两种药物间的相互作用,超过两种以上的药物所发生的相互作用比较复杂,故在此主要探讨两种药物间的不良相互作用,临床上常将一些药物合并,因此除发生药物相互作用外,还可能发生理化配伍变化。现将常用的处方药中易发生的配伍反应简述如下。
Various drugs acting alone on the human body, can produce their own pharmacological effects. When the combination of multiple drugs, due to their interaction, can enhance the efficacy or reduce side effects, but also can reduce the efficacy or appear unwanted side effects, and even some specific adverse reactions, harm drug users . From the current level of view, in most cases can only explore the interaction between the two drugs, more than two kinds of drugs occur more complex interactions, it is mainly to explore the adverse interaction between the two drugs, clinically Some drugs are often combined, so in addition to drug interactions, but also changes in physicochemical compatibility may occur. Commonly used prescription drugs are prone to occur in the compatibility reaction is summarized as follows.