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目的探讨不同手术入路方式治疗第三脑室颅咽管瘤的临床治疗效果。方法选取2010年3月至2011年3月间收治的70例第三脑室颅咽管瘤患者,按照随机数字法分为A组和B组,每组35例。A组患者给予经皮质-侧脑室入路手术,B组患者给予经胼胝体-透明隔-穹窿间入路手术,观察两组患者的临床治疗效果。结果 A组患者肿瘤全切除率为77.1%,B组患者肿瘤全切除率为74.3%,两组差异无统计学意义(P>0.05)。A组患者手术时间和术中出血量分别为(127.3±23.5)min和(24.2±7.4)ml,B组患者手术时间和术中出血量分别为(121.6±24.1)min和(23.3±7.2)ml,两组差异无统计学意义(P>0.05)。A组患者术后并发症发生率为20.0%,B组为17.1%,两组差异无统计学意义(P>0.05)。结论对第三脑室颅咽管瘤患者采取经皮质-侧脑室入路手术和经胼胝体-透明隔-穹窿间入路手术治疗均具有较好的应用效果,临床可以选取这两种入路方式进行手术治疗,提高患者的临床治疗效果。
Objective To investigate the clinical effects of different surgical approaches for the treatment of craniopharyngioma in the third ventricle. Methods Seventy patients with third-ventricle craniopharyngiomas admitted from March 2010 to March 2011 were divided into group A and group B according to random number method, with 35 cases in each group. Patients in group A were given transcortical-lateral ventricle surgery. Patients in group B were given trans-corpus-translumenal-fornical approach to observe the clinical effect of the two groups. Results The total resection rate was 77.1% in group A and 74.3% in group B, with no significant difference between the two groups (P> 0.05). The operation time and intraoperative blood loss in group A were (127.3 ± 23.5) min and (24.2 ± 7.4) ml, respectively. The operation time and blood loss in group B were (121.6 ± 24.1) min and (23.3 ± 7.2) ml, no significant difference between the two groups (P> 0.05). The incidence of postoperative complications in group A was 20.0% and in group B was 17.1%. There was no significant difference between the two groups (P> 0.05). Conclusions The third ventricle craniopharyngioma patients with cortical - lateral ventricle surgery and translucent corpus callosum - transseptal intervertebral approach operation has a good effect, the clinical can choose these two ways to carry out Surgical treatment to improve the clinical treatment of patients.