论文部分内容阅读
目的:研究探讨新生儿肺炎的病原及临床特点。方法:对患儿呼吸道处的分泌物细菌进行培养,检测肺炎支原体和沙眼衣原体的荧光核酸。采用免疫荧光法检测呼吸道合胞病毒和副流感病毒1、2、3型以及腺病毒等。结果:对948例新生儿肺炎患者进行病原检测,其中呈阳性者296例(31.2%),细菌性病原者186例(62.8%),RSV肺炎患者80例(27.0%),副流感病毒3型患者6例(2.0%),CT肺炎患者22例(7.4%),MP患者2例(0.7%);检测呈阴性者652例(68.8%),G-杆菌占细菌总数的80.6%;G+球菌占19.4%。G-杆菌与G+球菌相比较,G-杆菌的检出率明显要高(P<0.05)。对胎龄不同及日龄儿进行检测,G-杆菌和G+球菌的检出率无显著性差异(P>0.05)。RSV肺炎一般在12月至次年5月间发病,临床表现有喘憋、肺部喘鸣音。CT肺炎患者进行阴道分娩者占90.9%,剖宫产者占9.1%。结论:新生儿肺炎的临床表现症状不典型,很难根据临床表现对病原做出正确判断,RSV肺炎是新生儿病毒性肺炎的一种常见病原。
Objective: To study the pathogens and clinical features of neonatal pneumonia. Methods: The bacteria in the respiratory tract of children were cultured and the fluorescence nucleic acids of Mycoplasma pneumoniae and Chlamydia trachomatis were detected. Respiratory syncytial virus and parainfluenza virus type 1, 2 and 3 and adenovirus were detected by immunofluorescence method. Results: A total of 948 neonates with pneumonia were tested for pathogens, of which 296 (31.2%) were positive, 186 (62.8%) were bacterial, 80 (27.0%) were RSV pneumonia, Six patients (2.0%), CT pneumonia in 22 patients (7.4%) and MP patients in two patients (0.7%); 652 patients (68.8%) were negative, G- bacteria accounted for 80.6% of the total number of bacteria; Accounting for 19.4%. The detection rate of G-bacilli was significantly higher in G-bacteria than in G-bacteria (P <0.05). There was no significant difference in the detection rate of G-bacteria and G-type bacteria between the gestational age and the day-old children (P> 0.05). RSV pneumonia generally onset between December to May next year, clinical manifestations of wheezing, lung wheezing. Patients with CT pneumonia underwent vaginal delivery accounted for 90.9%, cesarean section accounted for 9.1%. Conclusion: The clinical manifestations of neonatal pneumonia are not typical, it is difficult to make the correct judgment of the pathogen according to clinical manifestations. RSV pneumonia is a common pathogen of neonatal viral pneumonia.