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目的研究阿托伐他汀对脑梗死患者C-反应蛋白及预后的影响。方法 70例脑梗死患者随机分为2组,治疗组给予阿托伐他汀20mg,口服,1次/晚,疗程4周,观察治疗前后血清C-反应蛋白及神经系统功能缺损评分的变化。结果使用阿托伐他汀治疗后患者血清C-反应蛋白,显著降低,神经系统功能缺损评分好转。结论阿托伐他汀能够降低脑梗死患者的C-反应蛋白,从而改善脑梗死的预后。
Objective To study the effect of atorvastatin on C-reactive protein and prognosis in patients with cerebral infarction. Methods Seventy patients with cerebral infarction were randomly divided into two groups. The treatment group received atorvastatin 20 mg orally and once daily for 4 weeks. The changes of serum C-reactive protein and neurological deficit scores before and after treatment were observed. Results After treatment with atorvastatin, serum C-reactive protein was significantly decreased and neurological deficit scores improved. Conclusions Atorvastatin can reduce C-reactive protein in patients with cerebral infarction and thus improve the prognosis of cerebral infarction.