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[目的]观察痛风汤联合西药治疗原发性痛风疗效。[方法]使用随机平行对照方法,将70例门诊患者按就诊顺序简单随机分为两组。对照组32例吲哚美辛,25mg/次,3次/d;秋水仙碱,0.5mg/次,1次/d。治疗组38例痛风汤(黄柏、泽泻各10g,桂枝5g,苍术、海风藤、青风藤、秦艽、威灵仙各15g,滑石、车前子各20g,牛膝川、生薏苡仁各30g;痛风石且关节肿胀加姜黄;夜间关节剧痛加没药、土鳖虫、丹参、生地黄;关节畸形加浙贝母、穿山甲;下肢痹痛难耐加木瓜、独活、防己;初期发热恶风加防风;上肢痹痛加羌活);1剂/d,水煎400m L,早晚口服,200m L/次;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、血尿酸、血沉、C反应蛋白、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈15例,显效13例,有效8例,无效2例,总有效率94.74%。对照组痊愈10例,显效8例,有效7例,无效7例,总有效率78.13%。治疗组疗效优于对照组(P<0.05)。风湿指标两组均有改善(P<0.05),治疗组改善优于对照组(P<0.01)。[结论]痛风汤联合西药治疗原发性痛风疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of gout decoction combined with western medicine on primary gout. [Methods] Using randomized parallel control method, 70 outpatients were randomly divided into two groups according to the order of treatment. Control group, 32 cases of indomethacin, 25mg / times, 3 times / d; colchicine, 0.5mg / time, 1 time / d. Treatment group, 38 cases of gout soup (Treats, Alisma 10g, Cassia twig 5g, herb, sea buckthorn, Qingfeng vine, Gentiana, Clematis each 15g, talc, psyllium each 20g, Achyranthes, raw Coix Seed Each 30g; tophi and swelling of the joints plus turmeric; nocturnal joint pain and no myrrh, Eupolyphaga, Salvia, Rehmannia; joint deformity plus Fritillaria, pangolins; lower limbs Bitong pain hard with papaya, live alone, anti self; Wind plus wind; upper limb Bitong plus Notopterygium); 1 / d, decoction 400m L, morning and evening oral, 200m L / time; Western medicine treatment with the control group. Continuous treatment 7d for a course of treatment. Observation of clinical symptoms, serum uric acid, erythrocyte sedimentation rate, C-reactive protein, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Result] The treatment group cured 15 cases, markedly effective in 13 cases, effective in 8 cases, ineffective in 2 cases, the total effective rate was 94.74%. The control group recovered 10 cases, markedly effective in 8 cases, effective in 7 cases, ineffective in 7 cases, the total effective rate was 78.13%. The treatment group was better than the control group (P <0.05). Rheumatoid index improved in both groups (P <0.05), the treatment group improved better than the control group (P <0.01). [Conclusion] Gout Decoction combined with western medicine is effective in treating primary gout without serious adverse reactions and is worth promoting.