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目的：D－二聚体是交联纤维蛋白的特异性降解产物，与血液凝固、纤溶过程具有一定的内在联系。为了研究脑梗塞患者血液中D－二聚体含量的变化并证实脑梗塞时血液呈高凝状态。方法：本文采用定量酶联吸附法，测定45例脑梗塞患者的血浆D－二聚体含量，另选30例性别、年龄组成相似的健康人作为正常对照，所得数据以X±SD表示，用t显著性检验处理数据。结果：结果发现脑梗塞患者血浆D－二聚体含量明显高于对照组，两组比较有显著性差异（P＜0．05）。结论：本研究结果表明脑梗塞患者血浆D－二聚体含量增高，提示脑梗塞患者的血液呈高凝状态。D－二聚体测定对血栓性疾病的诊断具有实际的应用意义，同时可用于血栓性疾病溶栓治疗的监测指标。
OBJECTIVE: D-dimer is a specific degradation product of cross-linked fibrin, and has some inherent connection with blood coagulation and fibrinolysis. In order to study the changes of D-dimer levels in the blood of patients with cerebral infarction and to confirm the hypercoagulable state of blood in cerebral infarction. Methods: Quantitative enzyme-linked immunosorbent assay was used to determine plasma D-dimer levels in 45 patients with cerebral infarction. Another 30 healthy subjects with similar sex and age were selected as normal controls. The data obtained were expressed as X ± SD. t Significance test processing data. Results: The results showed that the content of plasma D-dimer in patients with cerebral infarction was significantly higher than that in the control group. There was significant difference between the two groups (P <0.05). Conclusion: The results of this study show that plasma D-dimer levels increased in patients with cerebral infarction, suggesting that the blood of patients with cerebral infarction hypercoagulable state. D-dimer assay for the diagnosis of thrombotic disease has practical significance, but also can be used for thrombotic thrombolytic therapy monitoring indicators.