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氯丙嗪(简称CPZ)具有广泛的药理作用,近年来进展颇大,现介绍如下: 一、治疗心衰:CPZ通过α受体阻滞作用使血管扩张,主要降低心脏的前负荷:其镇静止吐作用,可减少心肌氧耗;也可促进肾输出量,加强利尿剂的利尿效应。有人总结59例证明CPZ治疗心衰疗效确实,无副作用。我们治疗经常规疗法效果不好的急性左心衰4例,疗效亦佳。方法是5～10mg肌注或0.5mg/分静滴,待病情好转或接受CPZ达25mg为止。值得注意的是>25
Chlorpromazine (referred to as CPZ) has a wide range of pharmacological effects, considerable progress in recent years, are presented below: First, the treatment of heart failure: CPZ by α-blockade of blood vessels to make dilation, mainly to reduce the preload of the heart: the town Static spit role, can reduce myocardial oxygen consumption; can also promote renal output, diuretic to enhance diuretic effect. It was concluded 59 cases that CPZ treatment of heart failure effect is indeed no side effects. Our treatment of conventional therapy is not good in 4 cases of acute left heart failure, the effect is also good. The method is 5 ~ 10mg intramuscular injection or 0.5mg / min intravenous infusion, until the condition improved or receiving CPZ up to 25mg so far. It is worth noting that> 25