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目的慢性阻塞性肺病(COPD)患者常发生肺炎,但促使COPD患者发生肺炎的影响因素少有研究。本研究将对这些危险因素进行评估。方法对2015年1月1日-12月31日于天津市海河医院住院的121例COPD患者进行回顾性分析。收集这些患者的临床及影像学资料,对这些资料进行分析,探索COPD患者发生肺炎的危险因素。结果统计分析表明,共有10例患者(8.2%)发生肺炎,吸入支气管扩张剂后一秒用力呼气容积占预计值百分比(FEV1占预测值%)和计算断层扫描(CT)肺气肿程度(吸气V950)是发生肺炎的独立危险因素。[吸入支气管扩张剂后FEV1:风险比(HR),0.97;95%可信区间(CI),0.94~1.00;P=0.048;吸气V950:HR,1.04;95%CI,1.01~1.07;P=0.01]。结论吸入支气管扩张剂后FEV1及经CT测量肺气肿严重程度是COPD患者发生肺炎的重要的危险因素。
Objective Chronic obstructive pulmonary disease (COPD) patients often develop pneumonia, but there are few studies that have contributed to the development of pneumonia in COPD patients. This study will assess these risk factors. Methods A retrospective analysis of 121 COPD patients hospitalized in Haihe Hospital, Tianjin from January 1, 2015 to December 31, 2015 was conducted. The clinical and radiological data of these patients were collected and analyzed to explore the risk factors for developing pneumonia in COPD patients. Results Statistical analysis revealed pneumonia in 10 patients (8.2%), forced expiratory volume in one second after exposure to bronchodilator (% predicted FEV1) and degree of emphysema (CT) Inspiratory V950) is an independent risk factor for pneumonia. [Post-bronchodilator FEV1: risk ratio (HR), 0.97; 95% CI, 0.94-1.00; P = 0.048; inspiratory V950: HR, 1.04; 95% CI, 1.01-1.07; P = 0.01]. Conclusions FEV 1 after inhaled bronchodilator and the severity of emphysema measured by CT are the important risk factors of pneumonia in COPD patients.