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目的探讨提高活体亲属肾移植供者安全性策略。方法回顾性分析与22例供者安全性相关的年龄、既往史、术前检查、麻醉方式、取肾侧别、手术方法、术后随访等项目。结果 1例供者出现气胸,胸穿排气后气胸消失。22例供者术后血肌酐(135±18)μmoL/l,较术前明显增高,6～10天降至正常。供者平均住院日(7±3)天。6例供者术后出现微量蛋白尿,3个月后复查均消失。供者平均随访时间3年,最长随访时间为5.5年,肾功能正常,未出现高血压和蛋白尿。术后6个月、2年进行生活质量调查,分别有91%(20/22).86%(19/22)生活质量良好。结论通过严格的供体筛查,详尽的术前准备,细致的手术操作及正规的术后随访可以减少并发症,提高供者安全性。
Objective To explore strategies to improve the safety of donor living in renal transplant recipients. Methods Retrospective analysis of items related to the safety of 22 donors, such as age, past history, preoperative examination, anesthesia, side of the kidney, surgical methods and follow-up were retrospectively analyzed. Results 1 patient showed pneumothorax, pneumothorax disappeared after wearing chest. Serum creatinine (135 ± 18) μmoL / l in 22 donors was significantly higher than that before operation, and decreased to normal after 6 ~ 10 days. The average hospital stay for donors (7 ± 3) days. 6 patients with microalbuminuria after surgery, 3 months after the review disappeared. The average follow-up time of donor was 3 years, the longest follow-up time was 5.5 years, normal renal function, no hypertension and proteinuria. Quality of life survey was performed 6 months and 2 years after operation, respectively, with 91% (20/22) and 86% (19/22) respectively. Conclusion Strict donor screening, detailed preoperative preparation, detailed surgical procedures and regular postoperative follow-up can reduce complications and improve donor safety.