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现代临床应用的各种药物中,有50余种可导致纯感觉或感觉运动混合型神经病.本文所讨论的是目前仍在应用的、特别是近来已认识到或怀疑有神经毒性并能导致周围神经病的药物.这对指导用药、避免严重的神经损害甚为必要.实验研究已阐明了一些导致神经病药物的发病机理,但其基本机制仍欠明瞭.大多数病理过程主要是轴索变性,少数药物如心舒宁可致节段性脱鞘.有些药物作用机制
Of the various drugs used in modern clinical practice, there are more than 50 different types of medications that can cause either pure or sensory motor-mixed neuropathy.The current discussion in this article is still in use today, and in particular has recently become known or suspected of being neurotoxic and leading to peripheral Neurological medicine.This is necessary to guide the medication to avoid serious neurological damage.Experimental studies have elucidated some of the pathogenesis leading to neuropathy drugs, but its basic mechanism is still not clear.Most of the pathological process is mainly axonal degeneration, a few Drugs such as heart Shu Ning can cause segmental dehiscence. Some drugs mechanism of action