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目的:了解百色地区2004～2007年新生儿α-地中海贫血(地贫)携带率。方法:采用全自动电泳仪对2004～2007年在该院出生的新生儿脐血做血红蛋白电泳分析,并对Hb区带进行扫描定量分析。结果:2004、2005、2006和2007年α-地贫携带率分别是19.05%、14.97%、13.22%和17.94%。结论:百色地区地贫携带率均高于南宁、柳州和广东地区,在地贫高发区普遍开展新生儿血红蛋白病筛查,对优生优育提高人口素质具有重要意义。
Objective: To understand the carrier rate of α-thalassemia (thalassemia) in neonates in Baise area from 2004 to 2007. Methods: The hemoglobin electrophoresis analysis of umbilical cord blood of neonates born in this hospital from 2004 to 2007 was performed by using the automatic electrophoresis apparatus. The Hb band was scanned and quantified. Results: The carrier rates of α-thalassemia in 2004, 2005, 2006 and 2007 were 19.05%, 14.97%, 13.22% and 17.94%, respectively. CONCLUSION: The prevalence rates of thalassemia in Baise area are higher than those in Nanning, Liuzhou and Guangdong provinces. Screening for hemoglobin disease in newborns with high incidence of thalassemia is of great significance for improving the population quality of prenatal and postnatal care.