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目的探究了解卡维地洛治疗急性心肌梗死后左心室重构的临床改善效果。方法 100例急性心肌梗死患者,随机分为对照组和观察组,各50例。对照组患者接受常规急性心肌梗死药物治疗,观察组患者在对照组治疗基础上联合卡维地洛。对比两组患者临床治疗效果以及治疗前后左心室重构改善情况。结果观察组患者临床治疗总有效率高于对照组患者,差异有统计学意义(P<0.05);观察组患者治疗前后各项指标比较,差异有统计学意义(P<0.05);对照组患者治疗前后各项指标比较,差异无统计学意义(P>0.05);观察组治疗后各项指标优于对照组,差异有统计学意义(P<0.05)。随访期间两组患者发生心力衰竭事件几率比较,差异无统计学意义(P>0.05)。结论对急性心肌梗死患者在常规治疗基础上联合卡维地洛治疗,不但能够取得令人满意的临床治疗效果,而且可有效改善患者左心室重构,具有高效安全的优点,值得临床普及推广。
Objective To investigate the clinical effect of carvedilol on left ventricular remodeling after acute myocardial infarction. Methods 100 cases of acute myocardial infarction were randomly divided into control group and observation group, 50 cases each. Patients in the control group received conventional AMI, and patients in the observation group received carvedilol on the basis of the control group. The clinical efficacy and the improvement of left ventricular remodeling before and after treatment were compared between the two groups. Results The total effective rate of clinical treatment in the observation group was higher than that in the control group (P <0.05), and the difference was statistically significant (P <0.05) between the observation group and the control group Before and after treatment, there was no significant difference between each index (P> 0.05). The indexes of the observation group were better than the control group after treatment (P <0.05). There was no significant difference in the incidence of heart failure between the two groups during follow-up (P> 0.05). Conclusion The combination of carvedilol and conventional treatment in patients with acute myocardial infarction can not only achieve satisfactory clinical therapeutic effect, but also effectively improve left ventricular remodeling in patients with acute myocardial infarction, which has the advantages of high efficiency and safety and is worthy of clinical popularization.