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目的 :探索莴苣叶鲜汁 ( LSFJ)对离体平滑肌的作用。方法 :制备离体兔胸主动脉环、支气管环和小肠标本 ,记录给药后 3min或 5 min的张力变化。结果 :LSFJ对血管平滑肌、支气管平滑肌具有明显的舒张作用。 5 %、1 0 %和 1 5 %分别使其张力降低 1 3.4%、1 9.62 %、2 8.9%和 2 1 .0 %、40 .2 %、66.4% ;对小肠平滑肌收缩作用加强 ,分别使小肠标本张力增加 66%、71 %和 82 %。结论 :LSFJ具有扩张血管 ,减少血流阻力 ,降低动脉血压 ;舒张气管平滑肌 ,减少气道阻力 ;兴奋小肠平滑肌 ,促进小肠运动
Objective: To explore the effect of lettuce leaf juice (LSFJ) on isolated smooth muscle. Methods: Isolated rabbit aortic rings, bronchial rings and small intestine specimens were prepared and the changes of tension were recorded 3 min or 5 min after administration. Results: LSFJ had obvious relaxation effect on vascular smooth muscle and bronchial smooth muscle. 5%, 10% and 15% reduced their tension by 13.4%, 1 9.62%, 2 8.9% and 21.0%, 40.2% and 66.4%, respectively; contractile effect on small intestine smooth muscle was enhanced Intestinal tension increased 66%, 71% and 82%. Conclusion: LSFJ has the advantages of dilating blood vessels, reducing blood flow resistance, lowering arterial blood pressure, relaxing tracheal smooth muscle and reducing airway resistance, excitating small intestine smooth muscle and promoting small intestine movement