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目的:分析生化检验指标在肝硬化疾病诊断中的临床价值,以期提高肝硬化患者的诊断正确率。方法:以血清胆碱酯酶为研究指标,选取我院2012年9月—2013年9月收治的肝硬化患者70例,同时选取同时期来我院接受健康体检者70例,设为对照组。采用速率法对两组患者的血清胆碱酯酶进行测定,且测定血清中的ALT、AST、GGT。结果:肝硬化组血清胆碱酯酶的数值明显比急性肝炎组、慢性肝炎组、对照组低(P<0.05);急性肝炎组、慢性肝炎组和对照组间也存在差异,不具有统计学意义(P>0.05)。结论:血清胆碱酯酶可以明显反映肝细胞蛋白合成代谢状况,以它为研究指标的生活检验项目是可以有效诊断肝硬化疾病的。
Objective: To analyze the clinical value of biochemical tests in the diagnosis of cirrhosis, in order to improve the diagnostic accuracy of patients with cirrhosis. Methods: Seventy patients with cirrhosis admitted to our hospital from September 2012 to September 2013 were enrolled in this study. Serum cholinesterase was used as the index in the study. Seventy patients with healthy subjects in our hospital were selected as the control group . The rate of serum cholinesterase in two groups of patients were measured, and serum ALT, AST, GGT. Results: The values of serum cholinesterase in cirrhosis group were significantly lower than those in acute hepatitis group, chronic hepatitis group and control group (P <0.05). There was also difference between acute hepatitis group, chronic hepatitis group and control group, Significance (P> 0.05). Conclusion: Serum cholinesterase can obviously reflect the status of protein synthesis and metabolism in liver cells, and it can be used to diagnose cirrhosis diseases by using it as the life test item of research index.