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目的了解深圳市婴幼儿乙肝疫苗基础免疫效果。方法 2011年7月随机调查深圳市某社区均完成乙肝疫苗全程接种的婴儿和幼儿各60名,采用《新生儿乙肝疫苗免疫效果调查表》和《深圳市儿童乙肝疫苗免疫效果调查表》进行现场问卷调查,对乙肝疫苗基础免疫效果进行分析评价。结果 60名婴儿免疫后的抗-HBs抗体阳转率为86.67%(52/60),60名幼儿免疫后的抗-HBs抗体阳转率为76.67%(46/60)。结论目前婴幼儿乙肝疫苗的基础免疫具有良好免疫效果,但部分婴幼儿在乙肝疫苗初次全程免疫后无免疫应答,存在复种免疫的需求。
Objective To understand the basic immune effect of infant hepatitis B vaccine in Shenzhen. Methods In July 2011, a random survey was conducted in a community in Shenzhen. All 60 infants and young children were vaccinated through the whole course of hepatitis B vaccination. The scene of “Questionnaire on Immunization of Hepatitis B Vaccine in Newborns” and “Questionnaire on Immunization of Children Hepatitis B Vaccine in Shenzhen” Questionnaire, hepatitis B vaccine based on the analysis of immune effects. Results The positive rate of anti-HBs antibody in 60 infants was 86.67% (52/60) after immunization, and the positive rate of anti-HBs antibody in 60 infants was 76.67% (46/60) after immunization. Conclusion At present, the basic immunity of infants and young children’s hepatitis B vaccine has a good immune effect, but some infants and young children have no immune response after the initial whole-dose immunization of hepatitis B vaccine and there is a need for multiple vaccination.