We take H+ 4-CO as a prototype to analyze the effect of ion or proton collision on molecular orientation modulated by a two-color shaped pulse combined with the time-delayed terahertz[THz]pulse.Through examining the effect of ion collision on the molecular orientation,we found that when the impact parameter and collisional velocity have weak inverse influences on the maximal orientation degree,the appropriate two-color and THz field intensity employed can improve the molecular orientation degree.The carrier envelope phase and frequency of the THz laser pulse as well as the temper-ature also have certain influence on the collision-induced molecular orientation.