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本文评价了血清脂质结合唾液酸(LSA)测定对肺部良、恶性疾病的鉴别诊断的意义。确定19.78mg NANA/dl为鉴别阳性、阴性的临界值,102例健康对照组LSA水平为13.8±3.70mg/dl,特异度为97.06％。104例肺癌组LSA水平为27.1±7.88mg/dl,敏感度为93.27％。55例良性疾患组为17.1±5.09mg/dl,特异度为89.09％。三组间LSA水平差异均有高度显著性,P<0,0001。
This article evaluated the significance of serum lipid-associated sialic acid (LSA) assay for differential diagnosis of benign and malignant lung disease. The critical value of 19.78 mg NANA/dl was identified as positive and negative. The LSA level in 102 healthy controls was 13.8±3.70 mg/dl with a specificity of 97.06%. The LSA level in 104 lung cancer patients was 27.1±7.88 mg/dl, and the sensitivity was 93.27%. 55 cases of benign disease group was 17.1±5.09 mg/dl with a specificity of 89.09%. The difference in LSA levels between the three groups was highly significant, P<0,0001.