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大多数周围神经的肿瘤都是Schwann细胞活跃增殖的结果。神经鞘瘤是一种良性孤立性有包膜的特殊类型肿瘤。本文报告我院近10年手术切除及病检确诊的26例(良性22例,恶性4例)神经鞘瘤。由于本瘤较罕见,故术前只2例诊断正确。18例(70％)随访平均62个月。4例(良性3例,恶性1例)于术后短期内复发,均因治疗过晚或已有恶变,或与未能彻底切除有关。虽文献介绍神经鞘瘤基本上都是良性,但本组4例(15.4％)恶变。故作者建议应将此瘤看作是有潜在恶变可能的良性瘤,最好尽早手术切除。
Most peripheral nerve tumors are the result of active proliferation of Schwann cells. Schwannoma is a benign, isolated, enveloped, special type of tumour. This article reports 26 cases (benign 22 cases, malignant 4 cases) of schwannoma diagnosed by surgical resection and pathological examination in our hospital in the past 10 years. Because this tumor is rare, only 2 cases were correctly diagnosed before surgery. Eighteen patients (70%) were followed for an average of 62 months. Four cases (3 benign and 1 malignancy) recurred in the short term after surgery, both because of late treatment or with malignant transformation, or because they were not completely removed. Although the literature describes that the schwannomas are basically benign, 4 cases (15.4%) were malignant in this group. Therefore, the authors suggest that this tumor should be regarded as a benign tumor with potential malignant transformation, and it is best to remove it as soon as possible.