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对生物活性物质的药动学（PK）一药效学（PD）相关性进行统计分析，可获得药物的一般测量值（如血浆浓度）与药理效能之间的明确关系。这在新药筛选、药品开发以及剂型优化等方面极为重要。常用的PK－PD模拟分析方法有连接模型法（linkmodel）和间接响应模型法（Indirectrespon
A statistical analysis of the pharmacokinetic (PK) -pharmacological (PD) correlation of bioactives gives a clear relationship between the general measure of drug (eg, plasma concentration) and pharmacological efficacy. This is extremely important in new drug screening, drug development and dosage form optimization. The commonly used PK-PD simulation methods include the link model and the indirect response model (Indirect response